Field 5 – Accelerated Translation into Personalised Oncology Clinical Practice
This field is specifically aimed at providing expert advice even to a single complex patient case or to a related finding or new discovery, so that patients can benefit from the results of cancer research possibly before the lengthy process of prospective clinical trials is completed. This field focuses on translational research aspects of MTBs.
| Unique ID | Country | Service Name | Description of Service | Research Infrastructure | Service Provider | Unit of access | Website |
|---|---|---|---|---|---|---|---|
| 6.2d_ECRIN | FR | Regulatory Support Services | Provide Regulatory Support to independent investigators to develop tailor-made regulatory plans for novel Personalised Oncology solutions | ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK (ECRIN) | ECRIN | 1 advice | https://ecrin.org/ |
| 6.2c_EATRIS | NL | Regulatory Support Services | The EATRIS regulatory service will provide assessment of the potential regulatory requirements required to prevent unnecessary project delays, reduce extra costs and most importantly prevent penalties resulting from non-adherence to legal requirements. EATRIS range of services include: • Expert opinion and regulatory strategy planning • Pre-clinical and clinical development plan including TPP and IMPD • Informal scientific advice with selected national competent authorities, for highly complex projectsAccess to information about the regulatory requirements, guidelines and legislations from 27 EU countries (as well as Norway, Switzerland, Turkey and Israel) regarding drug and medical device development derived from the application of European legislation through the EATRIS Regulatory Database. | EATRIS ERIC (EATRIS) | EATRIS | 1 advice | https://eatris.eu/ |
| 6.3_EATRIS | NL | Innovation support: Market analysis and IP guidance | The EATRIS Innovation Helpdesk helps life science researchers access real-time legal support and partnering advice from the EATRIS community. Our Innovation management services includes access to essential tools and resources for collaboration such as guidelines on intellectual property rights, open innovation and legal agreement templates. EATRIS Innovation Helpdesk services include: Real-time advice Template documents for frequently occurring technology transfer situations (MTA, CDA, etc) Guidelines and assistance with cross-infrastructure, industry/academia collaboration and knowledge sharing Access to specialist knowledge in relation to business development and legal and regulatory aspects On a case-by-case basis, hands-on involvement by Innovation Office staff with real collaboration and negotiation cases | EATRIS ERIC (EATRIS) | EATRIS | 1 advice | https://eatris.eu/ |
| 6.2a_D.Oncology | IT | Regulatory Support Services | Provide access to the EurOPDX infrastructure expertise in regulatory aspects related to generation, use and exchange of patient-derived cancer models, to support independent investigators in developing novel Personalised Oncology solutions. | EurOPDX (UNIVERSITA DEGLI STUDI DI TORINO) | University of Torino | 1 advice | https://www.oncology.unito.it/ |
| 6.2b_IC | FR | Regulatory Support Services | Provide access to the EurOPDX infrastructure expertise in regulatory aspects related to generation, use and exchange of patient-derived cancer models, to support independent investigators in developing novel Personalised Oncology solutions. | EurOPDX (UNIVERSITA DEGLI STUDI DI TORINO) | Institut Curie | 1 advice | https://institut-curie.org/ |
| 6.4* | AT,FR,IT,NL | Cancer Path Builder, a service to help users navigate the canSERV catalogue and elaborate complex projects involving multiple services. | The Cancer Path Builder (CPB) service is dedicated to tailoring research workflows across the canSERV service catalogue for a specific finding or a patient case. It allows cancer researchers to access expert advice from the various Research Infrastructures (RIs) and canSERV service providers. The user provides a complex project, requesting access to various canSERV services. After a first analysis of the user project, the Cancer Path Builder relies on experts in translational, preclinical, and clinical oncology from the various RIs and canSERV partners in order to provide advice on the user’s project to create a comprehensive and feasible research workflow leading to clinical applications. For example, Cancer Path Builder could be used for establishing the potential clinical relevance of a variant of unknown significance found in a given patient not only through database consultation and in silico analyses, but also through an experimental workflow including models, assays, advanced profiles, and more. | BBMRI-ERIC, EATRIS, ECRIN, UNITO, WU | BBMRI ECRIN EATRIS Curie UNITO WUR MMMI, NKI | 1 advice |
* This service will be offered by different service providers/beneficiaries. As soon as it´s requested, the board will decide on which service provider is the most suitable for the user.
More information about individual services, please contact us.